Table 3.
Total subjects | Low BMI | High BMI | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
HbA 1c level quintiles | HbA 1c level quintiles | HbA 1c level quintiles | ||||||||||
Q1 (low) | Q2 | Q3 (high) | P | Q1 (low) | Q2 | Q3 (high) | P | Q1 (low) | Q2 | Q3 (high) | P | |
No. at risk | 190 | 205 | 258 | 103 | 102 | 127 | 87 | 103 | 131 | |||
Age, year | 70.3 ± 6.3 | 70.5 ± 7.6 | 70.3 ± 6.7 | 71.5 ± 6.7 | 71.5 ± 8.1 | 70.2 ± 7.2 | 68.9 ± 5.6 | 69.5 ± 6.9 | 70.4 ± 6.1 | |||
Systolic blood pressure, mmHg | 144 | 147 | 143 | 0.187 | 140 | 142 | 140 | 0.721 | 149 | 152 | 147 | 0.223 |
Antihypertensive medication use, % | 35.9 | 30.1 | 38.9 | 0.132 | 27.4 | 24.8 | 30.3 | 0.642 | 46.1 | 35.2 | 47.0 | 0.144 |
Body mass index, kg/m2 | 22.8 | 23.5 | 23.1 | 0.062 | 20.8 | 20.9 | 20.8 | 0.674 | 25.1 | 26.0 | 25.4 | 0.008 |
Current drinker, % | 53.1 | 52.3 | 51.5 | 0.942 | 60.6 | 50.4 | 47.4 | 0.121 | 43.7 | 54.1 | 55.9 | 0.179 |
Current smoker, % | 20.5 | 17.6 | 24.0 | 0.242 | 23.8 | 21.0 | 29.2 | 0.334 | 16.8 | 14.5 | 18.7 | 0.692 |
Serum triglycerides, mg/dL | 97 | 119 | 105 | 0.003 | 91 | 101 | 92 | 0.284 | 105 | 137 | 117 | 0.010 |
Serum HDL-cholesterol, mg/dL | 56 | 54 | 56 | 0.319 | 60 | 56 | 58 | 0.157 | 51 | 52 | 54 | 0.321 |
Serum aspartate aminotransferase (AST), IU/L | 25 | 25 | 24 | 0.263 | 26 | 25 | 23 | 0.127 | 24 | 26 | 24 | 0.322 |
Glucose-lowering medication use, % | 2.1 | 2.0 | 1.2 | 0.699 | 3.9 | 3.0 | 0.8 | 0.279 | 0.0 | 1.0 | 1.6 | 0.481 |
Lipid-lowering medication use, % | 3.2 | 5.9 | 5.4 | 0.410 | 2.9 | 5.9 | 4.7 | 0.589 | 3.4 | 5.8 | 6.1 | 0.659 |
History of cardiovascular disease, % | 9.5 | 8.2 | 12.4 | 0.302 | 7.6 | 4.7 | 8.9 | 0.471 | 12.2 | 11.8 | 15.4 | 0.675 |
Taking medication for cardiovascular disease, % | 7.4 | 7.3 | 11.3 | 0.218 | 5.6 | 3.7 | 8.2 | 0.354 | 9.8 | 10.8 | 14.0 | 0.585 |
Serum creatinine, mg/dL | 0.98 | 0.92 | 0.92 | 0.055 | 1.00 | 0.93 | 0.92 | 0.193 | 0.96 | 0.91 | 0.93 | 0.334 |
Glomerular filtration rate (GFR), mL/min/1.73 m2 | 63.7 | 67.3 | 67.5 | 0.036 | 62.7 | 68.4 | 69.0 | 0.020 | 64.8 | 66.4 | 66.0 | 0.792 |
Age: mean ± standard deviation. Low BMI consists of BMI <23 kg/m2 and high BMI consists of BMI ≥23 kg/m2. P: age-adjusted values of P for the trend. BMI: body mass index.