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Proinflammatory cytokine response in peripheral blood mononuclear cells. Cytokine levels (IL-1β, IL-6, IL-8 and TNF) in control (WW) and TRAPS peripheral blood mononuclear cells maintained in culture for 24 (panel A) and 72 hours (panel B) and unstimulated or stimulated for 4 hours with LPS (1 μg/mL) (positive control), TNF (6 ng/mL) or IL-1β (1 ng/mL). Columns represent mean values ± SEM. *P <0.0001; °P <0.05; °°P <0.001 with respect to WW.
