Table 1.
Prevalence of comorbidities in patients with primary SS or RA and in age- and sex-matched healthy individuals
| SS (n = 64) | RA (n = 77) | HC (n = 60) | P -value* | P -value** | P -value*** | |
|---|---|---|---|---|---|---|
| Arterial wall thickening (IMT >0.90 mm), % | 59.4 | 63.8a | 40.4 | ns | <0.05 | <0.01 |
| IMT levels, mean ± SD | 1.0 ± 0.3 | 1.0 ± 0.4a | 0.9 ± 0.2 | ns | <0.05 | <0.01 |
| Presence of plaque, % | 68.8 | 84.4 | 56.9 | <0.05 | ns | <0.001 |
| Osteopenia, % | 51.6 | 54.2a | 36.8 | ns | ns | ns |
| Osteoporosis, % | 7.8 | 18.1a | 14.0 | ns | ns | ns |
| Osteoporosis/osteopenia, % | 59.4 | 72.2a | 50.9 | ns | ns | <0.05 |
| Fractures, % | 12.5 | 23.9a | 8.5 | ns | ns | <0.05 |
*Primary Sjogren's syndrome (SS) versus rheumatoid arthritis (RA); ** primary SS versus healthy controls (HC); *** RA versus HC; aanalysis based on 72 patients with RA. IMT, intima media thickness; ns, not significant.