Table 1.

Definition of the calculated parameters of the GVAP

Name	Formula	Symbols
Avg. AUC-H	$\frac{1}{T}{\displaystyle {\int }_0^T\left(G\left(t\right)-T{R}_H\right)dt,\mathrm{IF}\mathrm{G}\left(\mathrm{t}\right)>\mathrm{T}{\mathrm{R}}_{\mathrm{H}}}$	G (t) - Glucose–time function
		Target Range-High - TRH
		Avg. AUC-H - Average exposure to hyperglycemia.
		Avg. AUC-H = 10 mg/dL means that during the observation, on average the CGM glucose exceeded TRH limit by 10 mg/dL [23].
Avg. AUC-L	$\frac{1}{T}{\displaystyle {\int }_0^T\left(T{R}_L-G\left(t\right)\right)dt,\mathrm{IF}\mathrm{G}\left(\mathrm{t}\right)<\mathrm{T}{\mathrm{R}}_{\mathrm{L}}}$	G (t) Glucose - time function
		Target Range-Low - TRL
MAGE +/−	$\sum \frac{\lambda }{n}\mathrm{IF}\lambda >\mathrm{v}$	λ = amplitude of each glucose increase or decrease (nadir to peak / peak to nadir)
		n = number of observations
		ν = meaningful excursion (ME)
MAGE avg.
EF		MAGE+/−: mean of the upward/downward excursions
		MAGE avg.: average of MAGEs
		EF sum of all excursions [15,24,16]
MODD	$\frac{{\displaystyle {\sum }_{t=t_1}^{t_k}\left|B{G}_t-B{G}_{t-1440}\right|}}{k}$	BG: Blood Glucose
		k = number of observations where there is an observation at the same time 24 h (1,440 min) ago [25,26]
CONGA (n)	$\sqrt{\frac{{{\sum }^{t_k}}_{t=t1}{\left(D_t-\overline{D}\right)}^2}{k-1}}$	k = number of observations where there is an observation n × 60 min ago
	where Dt = BGt-BGt-m and	m = n × 60, in our program n = 1 [27,26]
	$\overline{D}=\frac{{{\sum }^{t_k}}_{t=t1}{D}_t}{k}$