TABLE 1.
Viral homologies found in human oncoproteins.
| Oncoprotein | Accession number of query sequence | E-value | Query coverage (%) | Taxon containing the homolog sequence | Viral group |
|---|---|---|---|---|---|
| Akt | NP_001014431.1 | 0 | 100 | AKT8 murine leukemia virus | Retroviridae |
| Src | P12931.3 | 0 | 100 | Avian sarcoma virus S1 | Retroviridae |
| PI3K | NP_006209.2 | 0 | 98 | Avian sarcoma virus 16 | Retroviridae |
| ABL | NP 005148.2 | 0 | 72 | Abelson murine leukemia virus | Retroviridae |
| RAF | P04049.1 | 0 | 57 | IC4 retrovirus | Retroviridae |
| EGFR | NP 005219.2 | 0 | 52 | Avian leukosis virus | Retroviridae |
| ROS1 | NP 002935.2 | 1–162 | 62 | UR2 sarcoma virus | Retroviridae |
| FGFR1 | NP_075598.2 | 6–151 | 81 | Feline sarcoma virus | Retroviridae |
| RET | P07949.3 | 5–146 | 39 | UR2 sarcoma virus | Retroviridae |
| MET | NP 001120972.1 | 1–131 | 23 | Avian erythroblastosis virus | Retroviridae |
| KRAS | NP 004976.2 | 3–122 | 100 | Kirsten murine sarcoma virus | Retroviridae |
| IGFR1 | NP 000557.1 | 5–122 | 33 | Avian sarcoma virus S1 | Retroviridae |
| DDR | NP 001945.3 | 2–115 | 38 | Avian sarcoma virus S1 | Retroviridae |
| FAK | Q05397.2 | 5–51 | 28 | Feline sarcoma virus | Retroviridae |
| IRAK1 | AAH54000.1 | 2–86 | 46 | Acanthamoeba poliphaga mimivirus | Mimiviridae (dsDNA vírus) |