Table 2. Scope of P450-Catalyzed C–H Amination with Carbonazidate Substrates[a].
Reactions conditions: 5 μM P450, 10 mM carbonazidate, cofactor regeneration system (100 μM NADP+, 1 μM phosphite dehydrogenase, 50 mM Na2PO3), 16 h. Turnover numbers (TON) were measured by HPLC from triplicate experiments.