Table 2.
Baseline characteristics of study participants
| Healthy Comparison Participants (n = 36) |
CHR Participants (n = 58)a |
AOP Participants (n = 20) |
p | |
|---|---|---|---|---|
| Age years (±SD) | 15.0 (1.5) | 15.5 (1.9) | 15.7 (1.6) | .37 |
| Participant education years (±SD) | 8.9 (2.2) | 8.9 (2.2) | 9.4 (1.8) | .33 |
| Parental education years (+SD) | 16.6 (2.8) | 16.7 (2.8) | 16.5 (1.9) | .94 |
| Gender N (% female) | 18 (50%) | 19 (33%) | 9 (55%) | .11 |
| Race (Native American/Asian/African | ||||
| American/Caucasian/other) | 1/4/5/17/9 | 1/7/4/37/9 | 0/3/2/7/8 | .41 |
| Ethnicity N (% Latino) | 7 (19%) | 14 (24%) | 3 (15%) | .66 |
| WASI IQ, two subtests (±SD) | 106.9 (15.9) | 103.8 (15.8) | 96.7 (13.4) | .10 |
| SRS overall T score | 47.8 (11.5) | 67.2 (14.9) | 70.7 (12.2) | <.001 |
| Global functioning | ||||
| Social | 8.6 (0.7) | 6.3 (1.6) | 5.5 (1.8) | <.001 |
| Role | 8.4 (0.9) | 5.9 (2.1) | 5.2 (1.7) | <.001 |
| SIPS | ||||
| Positive symptoms | 1.9 (2.1) | 11.6 (8.4) | 20.6 (4.7) | <.001 |
| Negative symptoms | 1.8 (1.9) | 11.2 (5.6) | 18.2 (6.0) | <.001 |
| Disorganized symptoms | 0.7 (0.9) | 5.6 (4.5) | 8.0 (4.2) | <.001 |
| General symptoms | 1.0 (1.3) | 8.2 (4.7) | 9.6 (4.1) | <.001 |
Note: CHR, clinical high risk; AOP, adolescent-onset psychosis; WASI, Wechsler Abbreviated Scale of Intelligence; SRS, Social Reciprocity Scale; SIPS, Structured Interview for Prodromal Symptoms.
a
Excluding three CHR subjects with autism spectrum diagnoses.