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The effect of CgTX titration on single action potential-evoked Ca2+ entry and neurotransmitter release (as measured by changes in quantal content)
| [CgTX], nM: | 25 | 50 | 75 | 100 | 400 | 600 |
|---|---|---|---|---|---|---|
| %Ca2+ entry blocked | 22 ± 1.0 | 41 ± 2.6 | 59 ± 4.6 | 70 ± 5.9 | 85 ± 8.0 | 92 ± 1.7 |
| %Vesicle release blocked | 34 ± 2.4 | 64 ± 2.9 | 79 ± 5.0 | 84 ± 1.8 | 96 ± 2.5 | 98 ± 1.4 |
Values are means ± SD.
