Fig. 5.
Dorsal CA1 neurons showed greater responses to A1 adenosine receptor (A1AR) antagonist compared with ventral CA1 neurons. A and E: time course of changes in Vm and Rin during 1,3-dipropyl-8-cyclopentylxanthine (DPCPX; 100 nM) wash-in experiments in dorsal (A) and ventral (E) neurons. B and F: representative voltage responses with step current commands at RMP are shown. C and D: DPCPX (100 nM) caused a significant depolarization in dorsal neurons (C) and an increased Rin (D). G and H: ventral neurons showed no changes in Vm (G) and Rin (H) after DPCPX (100 nM) wash-in. I and J: the changes in Vm (I) and Rin (J) after 100 nM DPCPX wash-in were greater for dorsal neurons than ventral neurons. *P < 0.05; #P < 0.05 vs. ventral group.