Table 1.
Baseline | 50 μM Ba2+ wash-in | 10 μM ZD7288 50 μM Ba2+ wash-in | |
---|---|---|---|
Dorsal CA1 | |||
Vm, mV | −69.7 ± 0.5 (n = 7) | −64.4 ± 1.0 (n = 7)* | −71.0 ± 0.7 (n = 7) |
Rin, MΩ | 60.8 ± 4.1 (n = 7) | 85.7 ± 5.6 (n = 7)* | 166.4 ± 9.0 (n = 7)* |
Ventral CA1 | |||
Vm, mV | −66.5 ± 0.7 (n = 7) | −64.8 ± 1.0 (n = 7) | −71.9 ± 1.5 (n = 7)* |
Rin, MΩ | 73.7 ± 8.3 (n = 7) | 84.8 ± 8.4 (n = 7) | 162.1 ± 12.7 (n = 7)* |
Ba2+, barium; CA1, Cornu Ammonis area 1; Vm, membrane potential; Rin, steady-state input resistance. Statistically significant (
P < 0.05, 1-way ANOVA, followed by Bonferroni post hoc test compared with baseline).