Table 6.
Subthreshold membrane properties in 5 μM CGP55845 or 100 μM baclofen wash-in experiments (related to Fig. 4)
| Dorsal CA1 | Baseline | 5 μM CGP55845 | Ventral CA1 | Baseline | 5 μM CGP55845 |
|---|---|---|---|---|---|
| Vm, mV | −70.0 ± 0.8 (n = 4) | −70.2 ± 0.9 (n = 4) | Vm, mV | −64.7 ± 0.4 (n = 4) | −64.2 ± 0.5 (n = 4) |
| Rin, MΩ | 62.7 ± 2.7 (n = 4) | 64.5 ± 3.3 (n = 4) | Rin, MΩ | 86.4 ± 4.0 (n = 4) | 89.6 ± 4.0 (n = 4) |
| Dorsal CA1 | Baseline | 100 μM Baclofen | Ventral CA1 | Baseline | 100 μM Baclofen |
|---|---|---|---|---|---|
| Vm, mV | −69.4 ± 1.6 (n = 6) | −76.6 ± 1.0* (n = 6) | Vm, mV | −66.1 ± 0.7 (n = 6) | −74.4 ± 1.0* (n = 6) |
| Rin, MΩ | 66.6 ± 5.7 (n = 6) | 46.5 ± 2.1* (n = 6) | Rin, MΩ | 83.2 ± 5.7 (n = 6) | 63.1 ± 3.4* (n = 6) |
Statistically significant (
*
P < 0.05, Student's paired t-test compared with baseline).