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. 2015 May 1;10(5):e0124554. doi: 10.1371/journal.pone.0124554

Table 1. Research centers description.

Characteristics of trial centres KHRC (Ghana) KWTRP (Kenya) CNRFP (Burkina Faso)
Year of establishment 1994 1989 1983
Location Brong Ahafo Region, middle belt of Ghana Kilifi County, Kenyan Coast Ouagadougou
Institutional size (research capacity) year 2012/13 Over 600 staff (120 researchers) Over 800 staff (77 researchers) Over 150 staff (57 researchers)
Year clinical trial facility established 2005 2007 2009
Examples of malaria clinical trials conducted RTS,S phase II and phase III malaria vaccine trials, Artemether-Lumefantrine malaria drug trial RTS,S phase II and phase III malaria vaccine trials, TrapVac trial, ME-Trap vaccine trial, Artemether-Lumefantrine malaria drug trial Phase IIb GMZ 2 malaria vaccine trial, Phase IIb ME-TRAP candidate malaria vaccine trial, Phase Ib MSP 3 candidate vaccine, Artemether-Lumefantrine malaria drug trial
Malaria transmission High endemic region Low endemic region Hyper-endemic with seasonal malaria transmission
Poverty levels 25% of its population in the lowest wealth quintile Over 60% of the population living below poverty lines Estimated to be at 40%
Literacy levels Over 52% with no formal education About 45% of adults unable to read and write Estimated to be at 21.8%
Main economic activities Subsistence farming Subsistence farming, small scale fishing and mining Subsistence farming, craft industries, fishing and local manufacturing
Predominant group(s) Akans (bonos) and Mos, Wangaras, Gonja and Mamprusi (Northern region) Mijikenda Goin, Karaboro and the Turka