Table 2. Effect of mycophenolate mofetil on modified Rodnan skin score.

Author	Duration of Therapy (months)	Mean baseline MRSS	Median baseline MRSS	MRSS at end of study	Level of significance
Stratton et al.[19]	12	28	NA	17	p < 0.001
Vanthuyne et al.[25]	12	20	NA	13	p < 0.0001 for all patients p = 0.002 for skin group
Nihtyanova et al.[27]	60	NA	26	11	NA
Le et al.[31]	12	24.4	NA	17.5	p < 0.001
Mendoza et al.[20]	Mean 18.2	24.56	NA	14.5	p = 0.0004
Derk et al.[21]	12	22.5	21.5	8.4	p < 0.0001
Koutroumpas et al.[29]	12	17.2	NA	17.7	p = 0.55
Herrick et al.[23]					p = 0.43
Protocol 1	36	NA	24	NA	–1.81 (95%CI—4.08, 0.460)
Protocol 2	36	NA	32	NA	–4.46 (95%CI—6.69, –2.23)
Protocol 3	36	NA	23.5	NA	–3.10 (95%CI—4.27, –1.93)