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. 2015 May 1;10(5):e0124888. doi: 10.1371/journal.pone.0124888

Fig 7. B-1CDP cells from IL-10 deficient mice are more competent to control L. major infection.

Fig 7

To confirm the production of IL-10 is involved in the susceptibility to infection by L. major, we used B-1CDP cells from IL-10 KO mice. When compared to B-1CDP from wild type mice, the cells from IL-10 KO mice are more resistant to infection. Our data demonstrate decreased in the number of intracellular amastigotes (A) and percentage of infected cells (B). We also observed the significant decrease in the liberated promastigotes forms by B-1CDP from IL-10 KO mice (C). Statistical analysis were performed by Student’ t test from representative results of three similar experiments and bars show the mean +SD. **p ≤ 0.05.