Table I. Donor characteristics.
HCMV− (n = 97) | HCMV+ (n = 55) | |
---|---|---|
Median age, y (range) | 32 (20–70) | 35 (21–77) |
Female sex, n (%) | 73 (75) | 32 (58) |
NKG2C genotype +/+, +/−, −/−, n (%) | 67/24/2 (72/26/2) | 35/17/2 (65/31/4) |
NKG2C− haplotype frequency (%) | 15.0 | 19.4 |
Median anti-HCMV IgG titer, IU/ml (range) | <0.25 | 394.2 (31.1–4411.6) |
Median anti-PT IgG titer, IU/ml (range) | 6.7 (0.5–139.3) | 5.0 (0.8–179.9) |
Median anti-H1N1 IgG titer, AEUs (range) | 214.6 (80.7–953.2) | 190.1 (90.2–522.7) |
Donors were classified as HCMV− and HCMV+ by anti-HCMV IgG ELISA, using 0.25 IU/ml as the cutoff per manufacturer’s instructions. NKG2 genotype (NKG2C+/+, NKG2C+/−, NKG2C−/−) was determined by PCR. IgG Ab titers against PT and H1N1 were calculated from interpolation of a reference serum or high-titer donor standard curve, respectively.