Table 1. SIV vRNA+ Cells in the Lungs of Macaques Infected with SIV ¹ .

Animal ID	DPI 2 at Necropsy	SIV Inoculation Route	plasma VL at Necropsy 3	vRNA+ cells in lungs 4
Uninfected Control
Rh4974	0	No	Negative	-
Rh4975	0	No	Negative	-
Rh4977	0	No	Negative	-
RhM097	0	No	Negative	-
RhM180	0	No	Negative	-
RhM179	0	No	Negative	-
Acute
A1	1	mac251, IR	Negative	-
A2	1	mac251, IR	Negative	-
B1	2	mac251, IR	Negative	-
B2	2	mac251, IR	Negative	-
C1	3	mac251, IR	Negative	-
C2	3	mac251, IR	Negative	-
C3	3	mac251, IR	Negative	-
Rh4971	3	mac251, IR	Negative	-
Rh4972	3	mac251, IR	Negative	-
Rh4973	3	mac251, IR	Negative	-
Rh5043	4	mac251, IR	Negative	-
Rh5044	4	mac251, IR	Negative	-
Rh4809	6	mac251, IR	Positive	+
Rh5052	6	mac251, IR	Positive	+
Rh5053	6	mac251, IR	Positive	+
RhL864	6	mac251, IR	Positive	+
30991	6	mac251, IVAG	Positive	+
31523	6	mac251, IVAG	Positive	+
29608	7	mac251, IVAG	Positive	+
34998	8	mac251, IVAG	Positive	+
28013	9	mac251, IVAG	Positive	+
24818	10	mac251, IVAG	Positive	+
Rh4976	10	mac251, IR	Positive	+
Rh4978	10	mac251, IR	Positive	+
Rh4979	10	mac251, IR	Positive	+
E1	12	mac251, IR	Positive	+
E2	12	mac251, IR	Positive	+
E3	12	mac251, IR	Positive	+
E4	12	mac251, IR	Positive	++
Chronic
F1	12 weeks	mac251, IR	Positive	+
F2	12 weeks	mac251, IR	Positive	++
F3	12 weeks	mac251, IR	Positive	+
F4	12 weeks	mac251, IR	Positive	++
29459	5 months	mac251, IVAG	Positive	++++
23756	5 months	mac251, IVAG	Positive	++++
25301	5 months	mac251, IVAG	Positive	+
27361	6 months	mac251, IVAG	Positive	+
25479	6 months	mac251, IVAG	Positive	++++

¹Totally 38 infected and 6 uninfected rhesus macaques were used in this study, and vRNA+ cells were quantified by ISH.

²DPI = Days post infection.

³Virus load in plasma was detected by real-time RT-PCR.

⁴SIV vRNA⁺ cells in lungs were detected using ISH with SIV-specific riboprobes:

−ith SIV-s⁺ cells/mm²

+, 5–50 vRNA⁺ cells/mm²

++, 51–100 vRNA⁺ cells/mm²

++++, >200 vRNA⁺ cells/mm².