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. 2015 May 1;10(5):e0123948. doi: 10.1371/journal.pone.0123948

Table 2. Correlation of butyrylcholinesterase activity within young patients and remaining age strata.

Young patients (45–64 years) Middle-aged and old patients (65–100 years)
values p = r = values p = r = p = *
Butyrylcholinesterase, kU/l (IQR) 7.2 (5.9–8.6) 6.2 (5.4–7.5) <0.001
LHD (max), U/l (IQR) 455.0 (294.0–753.0) 0.968 -0.003 444.5 (296.0–655.0) 0.216 0.061 0.367
CK (max), U/l (IQR) 950.0 (320.8–1752.5) 0.278 0.076 587.5 (225.3–1515.0) <0.001 0.207 0.003
Troponin T (max), μg/l (IQR) 2.2 (0.7–4.9) 0.529 -0.044 2.2 (0.8–4.9) 0.161 0.069 0.957
Gamma-GT μkat/l (IQR) 30.5 (20.0–53.8) 0.001 0.238 28.0 (18.0–48.0) 0.108 0.069 0.437
Quick Test % (IQR) 96.0 (82.3–109.8) 0.014 0.171 89.0 (75.0–101.0) <0.001 0.196 <0.001
Fibrinogen mg/dl (IQR) 388.5 (325.5–457.5) 0.003 0.204 421.0 (356.0–496.0) 0.280 -0.053 <0.001
Age, years (IQR) 54.3 (47.4–59.5) 0.055 0.134 84.4 (73.1–87.3) <0.001 -0.290 <0.001
Body mass index, kg/m2 (IQR) 28.1 (24.9–31.7) <0.001 0.252 25.3 (23.4–27.7) <0.001 0.185 <0.001
AST, U/l (IQR) 38.0 (24.0–98.0) 0.216 -0.086 49.0 (29.0–106.0) 0.393 -0.042 0.035
ALT, U/l (IQR) 27.0 (19.0–46.0) 0.113 0.110 27.0 (17.0–44.0) 0.037 -0.103 0.191
Total Bilirubin, μmol/l (IQR) 0.49 (0.35–0.70) 0.057 -0.134 0.62 (0.46–0.91) 0.001 -0.168 <0.001
Median BChE values (IQR) within Yes No Yes No p = **
Resuscitation before angiography 6.7 (5.3–7.5) 7.3 (5.9–8.7) 6.3 (5.1–8.0) 6.2 (5.5–7.4) 0.747
Hypertension 7.5 (5.9–9.1) 6.8 (5.3–8.0) 6.2 (5.4–7.5) 6.3 (5.5–7.4) <0.001
Diabetes mellitus 8.2 (6.4–9.5) 7.1 (5.9–8.4) 6.4 (5.2–7.3) 6.2 (5.5–7.7) <0.001
Hypercholesterolemia 7.3 (5.9–9.1) 6.8 (5.9–8.4) 6.4 (5.5–7.8) 6.1 (5.1–7.1) <0.001
Current smoker 7.3 (5.9–8.7) 6.7 (5.9–8.5) 6.3 (5.6–7.4) 6.2 (5.4–7.5) <0.001
Family history of CVD 7.2 (6.1–8.7) 7.2 (5.8–8.5) 6.1 (5.3–7.3) 6.3 (5.5–7.5) <0.001
STEMI 7.4 (6.1–8.7) 6.7 (5.4–8.4) 6.2 (5.4–7.5) 6.6 (5.8–7.8) <0.001
Coronary intervention 7.3 (5.9–8.7) 6.9 (5.0–8.4) 6.5 (5.6–7.9) 6.1 (5.2–6.9) <0.001
Fibrinolysis 6.5 (4.8–8.6) 7.3 (6.1–8.6) 5.8 (5.2–7.6) 6.3 (5.5–7.5) 0.759
Gender (male) 7.2 (5.9–8.5) 7.3 (5.9–8.6) 6.3 (5.5–7.7) 6.2 (5.3–7.4) 0.001

Continuous data are presented as median (interquartile range) and their association with butyrylcholinesterase was assessed using Spearman–Rho correlation coefficient. Median butyrylcholinesterase values are demonstrated within categorical data and were analyzed using Mann-Whitney-U test

* P-value for comparison of median values within young patients and the remaining age strata using Mann-Whitney-U test

** P-values for comparison of median butyrylcholinesterase values within categorical variables in young patients and the remaining age strata using Mann-Whitney-U test