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. 2015 May 1;10(5):e0124252. doi: 10.1371/journal.pone.0124252

Table 4. Hazard ratios of CCVD from fitting a Cox regression model (other factors).

Hazard Ratio of CCVD
Unadjusted Adjusted(e)
Gender: Female vs. male 0.97 (0.66, 1.43) 0.885 1.30 (0.75, 2.26) 0.346
Mode of HIV Transmission: Heterosexual contacts 1.00 1.00
IDU 0.92 (0.60, 1.41) 0.711 0.94 (0.44, 2.01) 0.869
Homosexual contacts 0.78 (0.50, 1.21) 0.267 0.92 (0.47, 1.77) 0.797
Other/Unknown 0.90 (0.41, 1.98) 0.796 0.94 (0.33, 2.70) 0.914
Ethnicity, Black vs. Caucasian 2.88 (1.51, 5.50) 0.001 4.82 (1.91, 12.16) <.001
CCVD diagnosis,Yes vs. No 3.07 (2.05, 4.60) <.001 1.35 (0.70, 2.60) 0.367
HBsAg, Negative 1.00 1.00
Positive 1.18 (0.80, 1.74) 0.398 1.70 (0.85, 3.37) 0.131
Not tested 1.13 (0.68, 1.88) 0.637 0.39 (0.11, 1.41) 0.152
HCVAb, Negative 1.00 1.00
Positive 1.18 (0.80, 1.74) 0.398 1.70 (0.85, 3.37) 0.131
Not tested 1.13 (0.68, 1.88) 0.637 0.39 (0.11, 1.41) 0.152
Calendar year of baseline per more recent 1.03 (0.98, 1.09) 0.246 0.97 (0.88, 1.07) 0.527
Age, years per 10 years older 1.90 (1.63, 2.21) <.001 1.78 (1.39, 2.30) <.001
CD4 count, cells/mmc per 100 higher 0.97 (0.91, 1.03) 0.280 1.06 (0.95, 1.19) 0.296
CD4 count nadir, cells/mmc per 100 higher 0.88 (0.81, 0.95) 0.001 0.86 (0.73, 1.01) 0.063
CD8 count, cells/mmc per 100 higher 1.00 (0.99, 1.01) 0.897 0.99 (0.96, 1.03) 0.703
Viral load, log10 copies/mL per log higher 0.94 (0.82, 1.07) 0.349 1.09 (0.89, 1.35) 0.392
ART-naive, Yes vs. No 0.66 (0.46, 0.95) 0.024 0.79 (0.43, 1.44) 0.437
Diabetes, Yes vs. No 1.81 (0.74, 4.43) 0.192 0.53 (0.15, 1.89) 0.329
Smoking, No 1.00 1.00
Yes 1.25 (0.85, 1.82) 0.253 1.41 (0.84, 2.36) 0.193
Unknown 0.80 (0.45, 1.42) 0.442 1.99 (0.73, 5.42) 0.180
Total cholesterol, mg/dL per 100 higher 1.42 (0.99, 2.03) 0.054 1.32 (0.79, 2.19) 0.290
HDL cholesterol, mg/dL per 100 higher 0.17 (0.04, 0.77) 0.022 0.19 (0.03, 1.13) 0.068
Use of statins, Yes vs. No 3.95 (2.00, 7.77) <.001 1.35 (0.50, 3.63) 0.552
Use of blood pressure lowering drugs, Yes vs. No 5.37 (3.22, 8.95) <.001 2.16 (0.96, 4.86) 0.062
Blood glucose, mg/dL per 100 higher 1.28 (0.66, 2.49) 0.470 0.83 (0.29, 2.41) 0.737