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. 2015 May 1;10(5):e0125928. doi: 10.1371/journal.pone.0125928

Fig 1. The effects of HIV PIs on HNSCC cell growth.

Fig 1

Human HNSCC cell lines SQ20B and FaDu were cultured in complete medium and treated with different concentrations of HIV PIs (Lopinavir/Ritonavir, L/R, 0–50 μM) or Thapsigargin (TG, 50 nM) for 48h. At the end of treatment, cell viability was assessed using the CCK-8 kit according to the instructions provided by the manufacturer. Relative numbers of viable cells were calculated. (A) SQ20B; (B) FaDu. Values of each group are mean ± S.E. of six independent experiments. *** P<0.001, Statistical significance relative to control group.