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. 2015 May 1;10(5):e0125928. doi: 10.1371/journal.pone.0125928

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© 2015 Liu et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 2 — Human HNSCC cells (SQ20B and FaDu) were cultured in complete medium and treated with different concentrations of HIV PIs (L/R, 12.5μM or 25μM) for 24h. At the end of treatment, cells were exposed to 2Gy or 4Gy of radiation. After irradiation, cells were detached and plated for colony-formation assays to assess clonogenic survival as described in “Methods”. Relative numbers of survival colonies are presented. (A) SQ20B; (B) FaDu; Values are mean ± S.E. of three independent experiments. ** P<0.01, *P<0.05, Statistical significance relative to control group.