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. 2015 May 1;10(5):e0125928. doi: 10.1371/journal.pone.0125928

Fig 4. Effect of HIV PIs on protein levels of the UPR genes in HNSCC.

Fig 4

HNSCC cells, SQ20B and FaDu, were cultured in complete medium and treated with different concentrations of L/R (0, 12.5, 25, and 50 μM) or TG (50 nM) for 24h. At the end of treatment, nuclear proteins were isolated. The protein levels of CHOP, ATF-4, XBP-1 and lamin B were determined by Western blotting analysis. Lamin B was used as a loading control. Representative images of immunoblots are shown. Values are mean ± S.E. of three independent experiments. Statistical significance relative to vehicle control, *P<0.05; **P<0.01. (A) SQ20B cells; (B) FaDu cells.