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. 2015 May 1;10(5):e0125420. doi: 10.1371/journal.pone.0125420

Table 3. Summary of all variants in LCL, B95.8, and Jijoye samples compared to EBV-1 and EBV-2.

Variants vs. EBV-1
Sample Total Insertion Deletion Substitution Intergenic Genic Noncoding Coding Synonymous Coding Non-Synonymous
LCL1 968 19 20 929 511 232 136 87
LCL3 606 14 10 582 327 167 59 52
LCL9 969 22 22 925 496 242 137 92
LCL10 980 14 20 946 576 227 110 65
Common LCLs 178 2 0 176 77 56 24 20
B95.8 73 5 5 63 39 8 10 16
Jijoye 1234 13 24 1197 710 215 176 108
Common LCLs+ B95.8+Jijoye 5 0 0 5 4 0 0 1
Variants vs. EBV-2
LCL1 645 9 9 627 115 226 167 137
LCL3 597 8 11 578 96 226 150 125
LCL9 639 10 9 620 113 238 158 130
LCL10 316 5 9 301 57 117 88 53
B95.8 530 6 10 514 79 206 121 115
Jijoye 423 3 5 415 90 129 123 81
Common LCLs 1,3,9 418 5 7 406 65 166 91 96
Common LCL10+ Jijoye 176 1 2 173 20 50 69 37
Common LCLs 1,3,9+ B95.8 317 3 4 310 43 139 66 69
Common ALL LCLs 85 0 2 83 15 18 28 24
Common ALL samples 49 0 0 49 7 15 16 11

Summary of the mutations identified in the LCLs and control samples when compared to EBV-1, we noted that substitution was the most common type mutation, with Jijoye having the most and B95.8 having the least. Deletions and insertions were also observed ranging from 5 (B95.8) to 24 (Jijoye) and 5 (B95.8) and 13 (Jijoye) respectively. When compared to EBV-2 it is to be noted that substitution was the most common type of mutation, with LCL1 (627) having the most and LCL10 (301) having the least. Deletions and insertions were also observed ranging from 5 (Jijoye) to 11 (LCL-3) for deletion and 3 (Jijoye) to 10 (LCL-9) for insertion respectively.