FIGURE 15.

CD44v7/8 and Hyal2 do not associate at the cell surface. Fibroblasts were grown to 70% confluence before growth arrest in serum-free medium for 48 h. Cells were then incubated under the various cytokine treatments according to experimental models as described under “Experimental Procedures.” Cells were subsequently fixed and stained for Hyal2 (red) and CD44v7/8 (green). Areas of co-localization appear as yellow, original magnification ×400. All images are representative of three individual experiments.