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. 2015 May 1;10(5):e0125281. doi: 10.1371/journal.pone.0125281

Fig 7. BIRC6 knockdown sensitized CRC cells to chemotherapy in a xenograft nude mouse model.

Fig 7

DLD-1 cells stably transfected with control shRNA and BIRC6 knockdown shRNA (59) were injected subcutaneously into nude mice. Tumorbearing mice were treated with CDDP (4 mg/kg; i.p., twice weekly). (A) The tumor size was monitored. (B) Total tumor weight of each group of mice was recorded. Data present Mean ± SEM of 5 mice of each group. *, P < 0.05; **, P < 0.01.