Fig 7. BIRC6 knockdown sensitized CRC cells to chemotherapy in a xenograft nude mouse model.
DLD-1 cells stably transfected with control shRNA and BIRC6 knockdown shRNA (59) were injected subcutaneously into nude mice. Tumorbearing mice were treated with CDDP (4 mg/kg; i.p., twice weekly). (A) The tumor size was monitored. (B) Total tumor weight of each group of mice was recorded. Data present Mean ± SEM of 5 mice of each group. *, P < 0.05; **, P < 0.01.