. Author manuscript; available in PMC: 2015 Oct 30.

Published in final edited form as: Nature. 2015 Feb 18;520(7549):670–674. doi: 10.1038/nature14125

Table 1. Subject characteristics.

	MRCA (discovery)	PAPA (1st replication)	SLSJ (2nd replication)
Number	355	149	160
Age (Mean, range)	28, 2-61	21, 18-30	29, 5-79
N (%) Female	172 (48.5%)	72 (48.3%)	80 (50.0%)
N (%) Asthmatic	175 (49.3%)	34 (22.8%)	69 (43.1%)
N (%) Smokers	45 (12.7%)	33 (22.1%)	28 (17.5%)
Eosinophil count (mean ± SE) per mcl ^*	406±383	246±214	242±205
Geometric Mean Serum IgE (Range) IU/L ^¶	320, 1-4999	663, 0-18800	412, 2-7653

Normal range <350 cells per mcl;

^¶

Normal range <100 IU/L