Table 3.

Association of peak C-peptide with CGM-measured CV

Visit	n	Univariate				Adjusted for IDAA1c
		Slopea	Intercept	p value	Correlationb	Slopea	Intercept	p value	Correlationc
3 months	58	−0.19±0.33	0.72	0.57	−0.26	0.04±0.33	1.12	0.91	−0.17
6 months	57	−1.02±0.41	0.93	0.02	−0.38	−0.19±0.43	1.33	0.67	−0.15
9 months	58	−1.60±0.45	1.06	<0.001	−0.45	−1.12±0.37	1.61	0.004	−0.40
12 months	55	−0.65±0.59	0.72	0.28	−0.14	0.54±0.47	1.43	0.26	0.07
18 months	43	−1.65±0.56	1.00	0.006	−0.53	−0.32±0.58	1.46	0.58	−0.24
24 months	30	−0.64±0.68	0.57	0.35	−0.12	−0.31±0.43	1.76	0.47	−0.14
Pooled (within-subject)d	301	−0.12±0.08	NAe	0.14	NA	−0.01±0.08	NAe	0.91	NA
Pooled (between-subject)f		−1.19±0.50	NAe	0.02	NA	−0.80±0.59	NAe	0.18	NA

^aSlope is expressed as mean±SD.

^bSpearman rank correlation

^cSpearman partial correlation adjusted for IDAA_1c

^dLongitudinal repeated measures regression model for within-subject effects from 3 months to 18 months

^eIntercept varies by visit

^fLongitudinal repeated measures regression model for between-subject effects from 3 months to 18 months