Table 4. The number of islet autoantibodies is associated with a higher odds of SH and failure to achieve HbA1c <6.0 (42 mmol/mol).
Model | Odds of SH accompanied by failure to achieve HbA1c <6.0% (42 mmol/mol; OR [95% CI]) | ||||
---|---|---|---|---|---|
|
|||||
No Autoantibodies | One autoantibody | p value | ≥Two autoantibodies | p value | |
Model 1a | 1 (Reference) | 4.0 (3.0, 5.3) | <0.0001 | 12.4 (7.1, 21.6) | <0.0001 |
Model 2b | 1 (Reference) | 3.3 (2.4, 4.6) | <0.0001 | 9.2 (5.2, 16.5) | <0.0001 |
Model 3c | 1 (Reference) | 3.4 (2.4, 4.7) | <0.0001 | 9.9 (5.4, 18.0) | <0.0001 |
Model 1 is unadjusted
Model 2 is Model 1 with additional adjustment for age, BMI and diabetes duration
Model 3 is Model 2 re-analysed by removal of any cases who died (n=21) and their respective controls (n=86)