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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Neurobiol Aging. 2015 Feb 18;36(5):1924–1937. doi: 10.1016/j.neurobiolaging.2015.02.011

Figure 3. Heat shock protein and co-chaperone expression in neo- and allocortical cultures.

Figure 3

Levels of the heat shock proteins Hsp90, Hsp70, Hsc70, HO1, Hsp25, Hsp60, and Hsp40 (A, E, F, G, H, I, J) and the co-chaperones CHIP, Hip, and Hop (B, C, D) in neo- and allocortical (entorhinal) cultures 24h after treatment with MG132, as measured by infrared two-color Western blotting. Allocortex exhibited greater MG132-induced increases in Hsp70, Hsc70, HO1, and Hsp25, but neocortex exhibited greater stress-induced increases in Hip and Hop. Shown are the mean ± SEM of 6 independent experiments. * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001 vs neocortex, + p ≤ 0.05, ++ p ≤ 0.01, +++ p ≤ 0.001 vs 0 μM MG132, ^ p ≤ 0.05, ^^ p ≤ 0.01 vs 0.125 μM MG132, LSD post hoc following two-way ANOVA.