Table 3.
Oxidative stress indicator, glutathione, and antioxidant enzyme activities in plasma and liver
| Control (n=9) | Homocysteine (n=9) | B6 deficient (n=9) | B6 supplement (n=9) | |
|---|---|---|---|---|
| MDA (µmol/L) | ||||
| Plasma | 3.53±0.64 | 3.43±0.43 | 3.50±1.13 | 3.40±0.46 |
| Liver | 1.40±0.47b | 1.37±0.46b | 3.33±1.45a | 1.18±0.55b |
| GSH (nmol/mg protein) | ||||
| Plasma | 0.56±0.20a | 0.32±0.09c | 0.43±0.18b | 0.26±0.03c |
| Liver | 15.39±3.15a | 11.50±0.79b | 9.07±1.26c | 9.72±2.12c |
| GPx (nmol/min/mg protein) | ||||
| Plasma | 21.21±2.02 | 20.89±3.84 | 21.51±1.36 | 22.44±2.81 |
| Liver | 332.94±43.31 | 299.11±47.93 | 315.31±18.69 | 348.57±55.29 |
| GR (nmol/min/mg protein) | ||||
| Plasma | 3.27±0.73a | 2.15±0.48b | 2.63±0.55b | 2.33±0.77b |
| Liver | 77.06±6.02b | 76.78±5.17b | 84.51±3.64a | 77.90±2.50b |
MDA, malondialdehyde; GSH, reduced glutathione; GPx, glutathione peroxidase; GR, glutathione reductase.
Values with different superscript letters are significantly different among groups; p<0.05.