Table 4.
Relation between high sensitivity C-reactive protein and location of cerebral white matter hyperintensities, headache characteristics, and sex differences in migraine patients*
| Parameters | hs-CRP (mg/L) | P ≤† | ||
|---|---|---|---|---|
| Juxtacortical WMHs | Present | 1.95 ± 2,22 | 1.13 (0.21 – 9.40) | NS |
| Absent | 1.94 ± 2,01 | 1.25 (0.10 – 9.92) | ||
| Subcortical WMHs | Present | 2.01 ± 2.20 | 1.35 (0.10 – 9.92) | NS |
| Absent | 1.91 ± 1,95 | 1.18 (0.19 – 9.80) | ||
| Periventricular WMHs | Present | 1.91 ± 0.83 | 2.04 (1.02 – 2.67) | NS |
| Absent | 1.94 ± 2.04 | 1.24 (0.10 – 9.92) | ||
| Sex | Female | 1.99 ± 2.14 | 1.21 (0.01 – 9.92) | NS |
| Male | 1.80 ± 1.62 | 1.35 (0.10 – 8.30) | ||
| Migraine disease duration (y) | ≤1 | 1.46 ± 2.04 | 0.75 (0.15 – 9.51) | NS |
| 2-6 | 1.92 ± 1.87 | 1.35 (0.10 – 9.40) | ||
| ≥7 | 2.10 ± 2.18 | 1.31 (0.10 – 9.92) | ||
| Headache duration (h) | r = -0.002 | NS | ||
| Visual analog score | r = -0.028 | NS | ||
| Headache frequency (no./mo) | r = 0.042 | NS | ||
*Data reported as mean ± SD, number of subjects (%), median (range, minimum to maximum), or correlation coefficient r between hs-CRP and parameters. Abbreviations: hs-CRP high sensitivity C-reactive protein, WMH white matter hyperintensity.
†NS, not significant (P > .05).