Table 1. Insertion and deletion counts.
| Polymerase variant | Wild type | L868M Pol α | L612M Pol δ | M644G Pol ϵ | ||||
|---|---|---|---|---|---|---|---|---|
| MMR status | + | − | + | − | + | − | + | − |
| Isolates | 8 | 5 | 6 | 7 | 8 | 4 | 8 | 6 |
| Passages | 240 | 142 | 180 | 178 | 240 | 90 | 240 | 158 |
| Generations | 7200 | 4260 | 5400 | 5340 | 7200 | 2700 | 7200 | 4740 |
| Mutations | Count | Count | Count | Count | Count | Count | Count | Count |
| −A or –T | 0 | 955 | 0 | 934 | 2 | 1382 | 3 | 1375 |
| −C or –G | 0 | 11 | 0 | 56 | 0 | 195 | 2 | 60 |
| +A or +T | 0 | 46 | 0 | 112 | 1 | 244 | 1 | 168 |
| +C or +G | 0 | 5 | 0 | 6 | 0 | 49 | 0 | 17 |
| >1-bp delete | 0 | 135 | 0 | 55 | 0 | 42 | 0 | 142 |
| >1-bp Insert | 0 | 8 | 0 | 10 | 0 | 3 | 0 | 11 |
Adapted from (11).