Table 2.
Presence of digestive symptoms, comorbidities, and percentiles for weight and height in patients with cystic fibrosis in a Brazilian referral center during the decades of 1990 to 2000 and 2000 to 2010
| Decade | Onset of digestive symptoms | p-value | OR | 95% CI | ||
|---|---|---|---|---|---|---|
| Presence | Absence | Total | ||||
| 1990–2000 | 62 (59.6%) | 42 (40.4%) | 104 | <0.001 | 0.295 | 0.17–0.51 |
| 2000–2010 | 151 (83.4%) | 30 (16.6%) | 181 | 1 | – | |
| Decade | Meconium ileus | p | OR | 95%CI | ||
| Presence | Absence | Total | ||||
| 1990–2000 | 6 (5.8%) | 98 (94.2%) | 104 | 0.021 | 0.35 | 0.11–0.91 |
| 2000–2010 | 27 (14.9%) | 181 | 1 | – | ||
| Decade | Diabetes mellitus | p | OR | 95%CI | ||
| Presence | Absence | Total | ||||
| 1990–2000 | 5 (4.8%) | 99 (95.2%) | 104 | 0.001 | 0.228 | 0.07–0.61 |
| 2000–2010 | 33 (18.2%) | 148 (81.8%) | 181 | 1 | – | |
| Decade | Fecal fat balance | p | OR | 95%CI | ||
| Presence | Absence | Total | ||||
| 1990–2000 | 71 (68.3%) | 33 (31.7%) | 104 | 0.031 | 0.534 | (0.31–0.93) |
| 2000–2010 | 145 (80.1%) | 36 (24.2%) | 181 | 1 | – | |
| Decade | Weight percentile | p | OR | 95%CI | ||
| P < 10 | P ≥ 10 | Total | ||||
| 1990–2000 | 73 (70.2%) | 31 (29.8%) | 104 | <0.001 | 4.206 | 2.34–7.67 |
| 2000–2010 | 35 (35.9%) | 63 (64.1%) | 98 | 1 | – | |
| Decade | Height percentile | p | OR | 95%CI | ||
| P < 10 | P ≥ 10 | Total | ||||
| 1990–2000 | 59 (56.7%) | 45 (43.3%) | 104 | 0.025 | 1.895 | 1.08–3.34 |
| 2000–2010 | 40 (40.9%) | 58 (59.1%) | 98 | 1 | – | |
P – percentile; p – p-value; OR – odds ratio; CI – confidence interval. Statistical analysis was performed by the χ2 test. Statistically significant values are indicated by bold font.