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. 2015 Apr 21;16:178. doi: 10.1186/s13063-015-0693-2

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© Møller-Bisgaard et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Intervention. The participants will be randomized 1:1 into either a treatment strategy based on DAS28 (control group) or a treatment strategy based on DAS28 and MRI (intervention group). Disease activity will be monitored systematically every 4 months by the CRP-based disease activity score (DAS28-CRP) (control and intervention groups) and presence of MRI BME (intervention group only).