Table 1.
Demographics and baseline characteristics
| MDD patients | Healthy participants | |
|---|---|---|
| Number | 32 | 25a |
| Age | 40.2 (11.2) | 38.8 (9.9) |
| Age range | 25.0-57.9 | 27.3-58.2 |
| Male | 19 (59.4 %) | 12 (48.0 %) |
| Ethnicity | ||
| White | 18 (56.3 %) | 15 (60.0 %) |
| Asian | 10 (31.3 %) | 3 (12.0 %) |
| African descent | 4 (12.5 %) | 7 (28.0 %) |
| Current alcohol use | 22 (68.8 %) | 19 (76.0 %) |
| Current tobacco use | 6 (18.8 %) | 1 (4.0 %) |
| HRSD-17 | 22.4 (2.7) | 0.5 (1.3) |
| HAMA | 21.1 (5.8) | 0.4 (0.9) |
| WAIS-III | 107.4 (11.2) | 109.2 (14.6) |
| CGI-S | 4.4 (0.6) | 1.0 (0.0) |
| PGI-S | 3.8 (1.1) | NA |
| SDS | 19.3 (5.4) | 0.2 (0.8) |
All values are presented as mean and standard deviation in parenthesis, except where indicated. Age is in years. Number of participants and percentage of participants are presented for Male gender, Ethnicity, Current alcohol and tobacco use. Total scores are presented for HRSD-17, HAMA, WAIS-III and SDS. Participants were matched by age (p = 0.62), gender (p = 0.39), and WAIS-III IQ (p = 0.61) with no significant difference between groups, similarly for alcohol (p = 0.55) and drug use (p = 0.12). Abbreviations: CGI-S, Clinician Global Impression of Severity scale; HAMA, Hamilton Anxiety Rating Scale; HRSD-17, 17-item Hamilton Rating Scale for Depression; MDD, major depressive disorder; NA, not applicable; PGI-S, Patient Global Impression of Severity scale; SDS, Sheehan Disability Scale; WAIS-III, Wechsler Adult Intelligence Scale third UK edition.
aexcluding 3 inadvertently enrolled healthy participants who did not meet entry criteria.