Table 3.
The distribution of polymorphisms in the case and control groups
| SNP | Allele frequency | Genotype frequency | p -value | ||||
|---|---|---|---|---|---|---|---|
| Wild type | Heterozygote | Mutant | |||||
| DRD1 rs4532 | Control | C (0.06) | T (0.94) | CC (0.02) | TC (0.07) | TT (0.90) | 0.26 |
| Case | C (0.24) | T (0.76) | CC (0.06) | TC (0.37) | TT (0.57) | ||
| DRD1 rs4867798 | Control | T (0.68) | C (0.32) | TT (0.42) | TC (0.52) | CC (0.06) | 0.35 |
| Case | T (0.54) | C (0.46) | TT (0.36) | TC (0.36) | CC (0.28) | ||
| DRD1 rs265981 | Control | T (0.18) | C (0.82) | TT (0.03) | TC (0.32) | CC (0.66) | 0.51 |
| Case | T (0.21) | C (0.79) | TT (0.02) | TC (0.36) | CC (0.66) | ||
| DRD2/ANKK1 rs1800497 | Control | C (0.48) | T (0.52) | TT (0.30) | TC (0.44) | CC (0.26) | 0.27 |
| Case | C (0.71) | T (0.29) | TT (0.09) | TC (0.40) | CC (0.51) | ||
| DRD3 rs3732783 | Control | T (1.00) | C (0.00) | TT (1.00) | TC (0.00) | CC (0.00) | 0.0014** |
| Case | T (0.95) | C (0.05) | TT (0.94) | TC (0.02) | CC (0.04) | ||
| DRD3 rs6280 | Control | C (0.24) | T (0.76) | CC (0.05) | TC (0.50) | TT (0.57) | 0.61 |
| Case | C (0.33) | T (0.76) | CC (0.08) | TC (0.38) | TT (0.42) | ||
| GRIN2B rs7301328 | Control | G (0.50) | C (0.50) | GG (0.57) | CG (0.38) | CC (0.05) | 0.47 |
| Case | G (0.28) | C (0.72) | GG (0.42) | CG (0.50) | CC (0.08) | ||
Data were analysed using Fisher’s exact test. ** , p < 0.01, which indicates a statistically significant difference.