Table 5.
Without imputed data | With imputed data | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Threshold value, x | No. studies with this threshold | Summary estimate | 95% CI | Tau | No. studies with this threshold | Summary estimate | 95% CI | Tau | ||
Lower | Upper | |||||||||
Lower | Upper | |||||||||
Sensitivity | ||||||||||
0.13 | 1 | 0.897 | 0.756 | 0.961 | 0.000 | 1 | 0.897 | 0.756 | 0.961 | 0.000 |
0.14 | 2 | 0.910 | 0.841 | 0.951 | 0.000 | 3 | 0.955 | 0.801 | 0.991 | 1.147 |
0.15 | 5 | 0.944 | 0.901 | 0.969 | 0.067 | 6 | 0.937 | 0.909 | 0.957 | 0.001 |
0.16 | 3 | 0.960 | 0.831 | 0.991 | 0.850 | 6 | 0.925 | 0.890 | 0.950 | 0.091 |
0.17 | 3 | 0.909 | 0.860 | 0.942 | 0.000 | 5 | 0.911 | 0.879 | 0.935 | 0.000 |
0.18 | 3 | 0.873 | 0.816 | 0.914 | 0.000 | 5 | 0.894 | 0.860 | 0.920 | 0.000 |
0.19 | 4 | 0.902 | 0.851 | 0.936 | 0.000 | 6 | 0.889 | 0.855 | 0.917 | 0.096 |
0.2 | 6 | 0.875 | 0.828 | 0.910 | 0.234 | 8 | 0.886 | 0.839 | 0.921 | 0.312 |
0.21 | 3 | 0.892 | 0.834 | 0.931 | 0.000 | 7 | 0.882 | 0.848 | 0.909 | 0.000 |
0.22 | 1 | 0.983 | 0.782 | 0.999 | 0.000 | 5 | 0.899 | 0.761 | 0.961 | 0.669 |
0.23 | 1 | 0.950 | 0.786 | 0.990 | 0.000 | 5 | 0.870 | 0.766 | 0.932 | 0.534 |
0.24 | 2 | 0.877 | 0.575 | 0.974 | 0.973 | 5 | 0.850 | 0.756 | 0.912 | 0.473 |
0.25 | 2 | 0.953 | 0.832 | 0.988 | 0.000 | 5 | 0.850 | 0.759 | 0.910 | 0.442 |
0.28 | 2 | 0.818 | 0.531 | 0.947 | 0.837 | 5 | 0.818 | 0.715 | 0.890 | 0.473 |
0.3 | 4 | 0.938 | 0.829 | 0.979 | 0.975 | 7 | 0.893 | 0.773 | 0.954 | 1.076 |
0.31 | 1 | 0.883 | 0.713 | 0.959 | 0.000 | 5 | 0.780 | 0.689 | 0.851 | 0.362 |
0.32 | 1 | 0.850 | 0.675 | 0.939 | 0.000 | 5 | 0.781 | 0.687 | 0.853 | 0.363 |
0.35 | 1 | 0.833 | 0.562 | 0.951 | 0.000 | 4 | 0.733 | 0.641 | 0.809 | 0.296 |
0.39 | 2 | 0.662 | 0.530 | 0.772 | 0.320 | 4 | 0.699 | 0.607 | 0.778 | 0.278 |
0.4 | 2 | 0.720 | 0.650 | 0.780 | 0.000 | 3 | 0.724 | 0.661 | 0.779 | 0.000 |
0.45 | 1 | 0.700 | 0.436 | 0.876 | 0.000 | 3 | 0.691 | 0.627 | 0.748 | 0.000 |
0.49 | 1 | 0.842 | 0.774 | 0.893 | 0.000 | 2 | 0.657 | 0.590 | 0.718 | 0.000 |
0.5 | 2 | 0.844 | 0.433 | 0.975 | 1.230 | 2 | 0.844 | 0.433 | 0.975 | 1.230 |
Specificity | ||||||||||
0.13 | 1 | 0.651 | 0.570 | 0.724 | 0.000 | 1 | 0.651 | 0.570 | 0.724 | 0.000 |
0.14 | 2 | 0.671 | 0.597 | 0.736 | 0.000 | 3 | 0.624 | 0.524 | 0.714 | 0.250 |
0.15 | 5 | 0.562 | 0.366 | 0.740 | 0.795 | 6 | 0.583 | 0.421 | 0.728 | 0.717 |
0.16 | 3 | 0.803 | 0.499 | 0.943 | 1.026 | 6 | 0.661 | 0.462 | 0.816 | 0.910 |
0.17 | 3 | 0.765 | 0.463 | 0.925 | 1.042 | 5 | 0.677 | 0.465 | 0.834 | 0.922 |
0.18 | 3 | 0.856 | 0.436 | 0.979 | 1.503 | 5 | 0.726 | 0.458 | 0.893 | 1.188 |
0.19 | 4 | 0.708 | 0.653 | 0.758 | 0.000 | 6 | 0.720 | 0.522 | 0.858 | 0.961 |
0.2 | 6 | 0.818 | 0.597 | 0.931 | 1.245 | 8 | 0.775 | 0.609 | 0.884 | 1.031 |
0.21 | 3 | 0.750 | 0.672 | 0.815 | 0.000 | 7 | 0.707 | 0.635 | 0.771 | 0.332 |
0.22 | 1 | 0.692 | 0.409 | 0.880 | 0.000 | 5 | 0.705 | 0.599 | 0.793 | 0.438 |
0.23 | 1 | 0.769 | 0.478 | 0.924 | 0.000 | 5 | 0.738 | 0.623 | 0.828 | 0.508 |
0.24 | 2 | 0.863 | 0.764 | 0.925 | 0.000 | 5 | 0.762 | 0.636 | 0.855 | 0.592 |
0.25 | 2 | 0.848 | 0.764 | 0.907 | 0.000 | 5 | 0.798 | 0.655 | 0.892 | 0.724 |
0.28 | 2 | 0.945 | 0.863 | 0.979 | 0.000 | 5 | 0.845 | 0.681 | 0.933 | 0.947 |
0.3 | 4 | 0.917 | 0.703 | 0.981 | 1.515 | 7 | 0.916 | 0.793 | 0.969 | 1.311 |
0.31 | 1 | 0.923 | 0.609 | 0.989 | 0.000 | 5 | 0.886 | 0.707 | 0.962 | 1.183 |
0.32 | 1 | 0.923 | 0.609 | 0.989 | 0.000 | 5 | 0.892 | 0.716 | 0.964 | 1.194 |
0.35 | 1 | 0.948 | 0.876 | 0.979 | 0.000 | 4 | 0.898 | 0.701 | 0.971 | 1.239 |
0.39 | 2 | 0.980 | 0.092 | 1.000 | 3.125 | 4 | 0.933 | 0.713 | 0.987 | 1.556 |
0.4 | 2 | 0.903 | 0.675 | 0.977 | 0.982 | 3 | 0.872 | 0.715 | 0.949 | 0.796 |
0.45 | 1 | 0.994 | 0.915 | 1.000 | 0.000 | 3 | 0.944 | 0.587 | 0.995 | 1.883 |
0.49 | 1 | 0.842 | 0.774 | 0.893 | 0.000 | 2 | 0.838 | 0.779 | 0.883 | 0.000 |
0.5 | 2 | 0.863 | 0.764 | 0.925 | 0.000 | 2 | 0.863 | 0.764 | 0.925 | 0.000 |
NB All meta-analyses used model (2), as model (1) often poorly estimated ρ 10t at +1 or -1.