Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Efficacy of rituximab and 2-CdA in the WSU-WM-SCID xenograft model
| Agent | Dose/(mg/kg), schedule | Route | Mice | T/C (%) | T-C Days | Log 10 kill | Cure |
|---|---|---|---|---|---|---|---|
| Control | Diluent, QD × 5 | i.v. | 8 | 100 | 0 | 0 | 0/8 |
| Rituximab | 150 mg, QD × 5 | i.v. | 8 | 30 | 13 | 1.9 | 0/8 |
| 2-CdA | 30 mg, QD × 5 | s.c. | 8 | 36.9 | 14 | 1.33 | 0/8 |
| (RTX + 2-CdA) | (150 + 30),QD × 5 | (i.v. + s.c.) | |||||
| Diluent | Diluent, QD × 5 | i.v. | 8 | 16.9 | N/A | N/A | 8/8 |
| (RTX + 2-CdA) | (150 + 30),QD × 5 | (i.v. + s.c.) |
