Table 4.

Effect of AHM and its fraction on acetic acid induced writhing

Groups	Drug (dose), route	No. of writhing (mean ± SEM)	% inhibition
Saline	10 ml/kg	70.38 ± 2.7	0
AHM	50 mg/kg,p.o.	27.65 ± 1.005***	60.71 ± 0.66
	100 mg/kg, p.o.	18.09 ± 1.24***	74.29 ± 1.20
	150 mg/kg, p.o.	16.15 ± 1.175***	77.05 ± 1.70
AHE	50 mg/kg,p.o.	18.25 ± 1.25***	74.06 ± 1.15
	100 mg/kg, p.o.	15.00 ± 1.00***	78.68 ± 1.05
	150 mg/kg, p.o.	12.75 ± 1.25***	81.88 ± 0.05
Diclofenac sodium	10 mg/kg, i.p.	13.22 ± 1.89***	81.65 ± 1.10
Aspirin	10 mg/kg, i.p.	20.13 ± 1.12***	71.39 ± 2.00

Data values shown represent mean ± SEM (n = 6). ***p < 0.001 versus only acetic acid treated group (One-way ANOVA followed by Tukey’s Multiple Comparison Test).