Table 1.
Results from bronchoalveolar lavage from dogs with chronic bronchitis that had or had not been to environmental tobacco smoke
| Unexposed dogs | Exposed dogs | |
|---|---|---|
| Number | 11 | 8 |
| Males:Females | 8:3 | 3:5 |
| Age(y) | 7.2 ± 2.5 | 8.6 ± 2.3 |
| Serum cotinine levels (ng/mL) | 0 (0–0) | 0.41 (0.03–1.42)* |
| Cells in BALF | ||
| Total nucleated cell counts (cells/μL) | 124 (57–231) | 600 (100–3175)* |
| Macrophages (%), | 56 (8–79) | 73 (50–92) |
| (cells/μL) | 56 (9–148) | 438 (50–2921)* |
| Neutrophils (%), | 21 (2–82) | 12 (0–27) |
| (cells/μL) | 30 (3–178) | 26 (0–345) |
| Lymphocytes (%), | 19 (3–54) | 7 (0–36) |
| (cells/μL) | 24 (2–78) | 35 (0–870) |
| Eosinophils (%), | 0 (0–4) | 0 (0–3) |
| (cells/μL) | 0 (0–4) | 0 (0–20) |
| Total DNA concentrations (ng/μL) | 7.0 (3.3–20.2) | 5.7 (2.4–29.4) |
| Corrected DNA concentrations (ng/μL) | 413 (158–1582) | 478 (112–743) |
| Rates of DNA methylation (%) | 11.4 (1.0–23.9) | 17.0 (9.5–42.7) |
*: significant differences between groups (p < 0.05).