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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Cancer Prev Res (Phila). 2015 Apr 14;8(5):387–399. doi: 10.1158/1940-6207.CAPR-14-0371

Figure 8. VDR and class I HDAC expression levels in human adenomas and adjacent normal colonic tissue.

Figure 8

A) Data from the NCBI GEO database (GDS2947) was downloaded and plotted to show VDR and HDAC expression in the matched samples. A significant down-regulation in VDR expression was observed in the adenomas, which is in contrast to the up-regulation of the class I HDACs (p<0.0001). B) VDR expression negatively correlated with HDAC2 and HDAC8 expression, and positively correlated with RXRA and SNAI2/SLUG in human adenomas. Correlations were signficant as determined by Pearson, with the p values indicated on the graphs.