Table 2.
Characteristics of patients for the qRT-PCR experiments.
| SR* | pAF | |
|---|---|---|
| Patients, n | 8 | 10 |
| Gender, m/f | 6/2 | 5/5 |
| Age, y | 64.5±3.0 | 67.5±3.8 |
| Body mass index, kg/m2 | 27.2±1.0 | 30.5±2.9 |
| CAD, n | 6 | 6 |
| MVD/AVD, n | 1 | 2 |
| CAD+MVD/AVD, n | 1 | 1 |
| Hypertension, n | 7 | 10 |
| Diabetes, n | 3 | 3 |
| Hyperlipidemia, n | 6 | 5 |
| LVEF, % | 55.0±6.0 | 44.6±6.2 |
| Digitalis, n | 1 | 2 |
| ACE inhibitors, n | 6 | 6 |
| AT1 blockers, n | 0 | 1 |
| β-Blockers, n | 6 | 6 |
| Dihydropyridines, n | 1 | 5 |
| Diuretics, n | 3 | 4 |
| Nitrates, n | 0 | 2 |
| Lipid-lowering drugs, n | 5 | 6 |
*
The qRT-PCR experiments included additional samples not used for the RNA-Seq and miR microarray experiments. Values are presented as mean±SEM or number of patients. SR, patients in sinus rhythm; pAF, paroxysmal atrial fibrillation patients; CAD, coronary artery disease, MVD/AVD, mitral/aortic valve disease; LVEF, left ventricular ejection fraction; ACE, angiotensin-converting enzyme; AT, angiotensin receptor. No statistical differences were found between SR and pAF groups using two-tailed Student’s t-test for continuous variables and Fisher’s exact test for categorical variables (all P>0.1).