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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Cancer Prev Res (Phila). 2015 Feb 23;8(5):444–454. doi: 10.1158/1940-6207.CAPR-14-0359

Figure 4.

Figure 4

Dietary CA-supplementation suppresses AOM/DSS-induced colon carcinogenesis in Nrf2+/+ but not Nrf2−/− mice. At the end of the treatment regimen, total tumor number (distal, middle, proximal combined) per mouse was determined as a function of treatment regimen. Horizontal lines indicate median values for every treatment group. CA-supplementation regimens (CA2 and CA11) caused a significant suppression of tumor multiplicity in Nrf2+/+ but not in Nrf2−/− mice (*p < 0.05; Mann-Whitney test; N.S.: not significant).