Table 1.

Data indicate median tumor number per mouse (including range from minimum to maximum) as a function of size (diameter in mm) and anatomical location (distal, middle, proximal) per experimental group (*p < 0.05 compared to ‘Nrf2^+/+ AOM/DSS’ group; Mann-Whitney test).

Groups		Nrf2 +/+			Nrf2 −/−
		AOM/DSS	CA2 AOM/DSS	CA11 AOM/DSS	AOM/DSS	CA2 AOM/DSS	CA11 AOM/DSS
Distal	<2mm	4.0 (2–7)	3.0 (3–5)	3.0 (1–9)	5.0 (4–6)	6.0 (5–8)	5.5 (4–8)
	≥2mm	3.0 (2–8)	1.0 (1–3)*	1.0 (1–2)*	2.0 (2–3)	2.0 (2–2)	2.5 (0–4)
Middle	<2mm	2.0 (0–5)	3.0 (2–4)	2.5 (0–5)	3.5 (2–5)	3.0 (2–4)	3.0 (2–5)
	≥2mm	2.0 (0–3)	1.0 (0–2)*	1.0 (0–2)*	2.0 (1–3)	2.0 (1–4)	2.0 (0–3)
Proximal	<2mm	3.0 (0–4)	0.5 (0–3)	0.0 (0–1)*	1.5 (0–3)	2.0 (0–2)	2.0 (0–3)
	≥2mm	1.0 (0–3)	0.0 (0–0)*	0.0 (0–0)*	0.0 (0–2)	0.0 (0–2)	0.5 (0–2)
Total		14.5 (12–20)	10.0 (8–12)*	9.0 (4–12)*	14.5 (13–18)	16.0 (12–20)	15.0 (12–19)