Table B4.
Alternative Interactions between BDNF, COMT, and APOE
| Dependent Variable: High School IQ
| |||
|---|---|---|---|
| (1) | (2) | (3) | |
| Panel A: BDNF + COMT | |||
| BDNF × COMT | 0.5647 (0.5068) | 0.5477 (0.5018) | −0.2785 (0.9250) |
| Standardized Birth Weight | 3.4547** (1.3849) | 3.5336*** (1.3462) | 5.0920** (2.0721) |
| G × E | −0.7729* (0.4546) | −0.8169* (0.4435) | −1.3350** (0.6701) |
| Controls | |||
| Demographic and Family SES | Y | Y | Y |
| Sibling Fixed Effects | N | N | Y |
| Estimation | |||
| Weighting by Prob. of Being in Sib Sample | N | Y | N |
| N | 938 | 938 | 938 |
| R Sqr. | 0.1351 | 0.1318 | 0.6985 |
|
| |||
| Panel B: BDNF + APOE | |||
| BDNF × APOE | −0.0980 (0.5973) | −0.1845 (0.6020) | 1.1247 (1.0024) |
| Standardized Birth Weight | 4.3016** (2.0475) | 3.5880* (2.0295) | 3.4296 (2.5690) |
| G × E | −0.8654 (0.5909) | −0.6508 (0.6058) | −0.6052 (0.7429) |
| Controls | |||
| Demographic and Family SES | Y | Y | Y |
| Sibling Fixed Effects | N | N | Y |
| Estimation | |||
| Weighting by Prob. of Being in Sib Sample | N | Y | N |
| N | 938 | 938 | 938 |
| R Sqr. | 0.1331 | 0.1285 | 0.6964 |
|
| |||
| Panel C: COMT + APOE | |||
| COMT × APOE | 0.7471 (0.5472) | 0.6330 (0.5456) | −0.8228 (0.8870) |
| Standardized Birth Weight | 4.6887*** (1.4842) | 5.3457*** (1.4782) | 4.7813** (1.8611) |
| G × E | −1.2046** (0.5042) | −1.4562*** (0.5024) | −1.2313** (0.6178) |
| Controls | |||
| Demographic and Family SES | Y | Y | Y |
| Sibling Fixed Effects | N | N | Y |
| Estimation | |||
| Weighting by Prob. of Being in Sib Sample | N | Y | N |
| N | 938 | 938 | 938 |
| R Sqr. | 0.1382 | 0.1366 | 0.6981 |
Notes: This table performs our base estimation (Table 4) with differing interactions between our 3 neuroplasticity genes. Panel A considers the additive score between BDNF and COMT, Panel B considers the additive score between BDNF and APOE, and Panel C uses the additive score between COMT and APOE.