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. Author manuscript; available in PMC: 2016 Jun 15.
Published in final edited form as: Mol Cell Endocrinol. 2014 Dec 8;408:165–177. doi: 10.1016/j.mce.2014.12.003

Fig. 5.

Fig. 5

Expression of Wdr63, a hypomethylated gene, in GDX-induced neoplastic cells of the adrenal cortex. A female DBA/2J mouse was gonadectomized at 3 weeks of age and adrenal tissue was harvested 3 mo later. Adjacent cryosections of adrenal tissue were stained with H&E (A) or subjected to in situ hybridization using a digoxigenin-labeled Wdr63 antisense riboprobe and alkaline phosphatase conjugated anti-digoxigenin antibody (B). Note that Wdr63 is expressed in neoplastic cells but not adjacent normal adrenocortical cells. Bar = 50 µm.