Table 2.
Risk of low FGLP-1, 1hGLP-1, and ∆GLP-1 levels for T2DM
| T2DM | NGT | OR (95% CI) | P | |
|---|---|---|---|---|
| Fasting state | ||||
| Low FGLP-1 (<2.21 pg/L) | 12 (60%) | 2 (10%) | 13,5 (2.434-74.867) | 0.001 |
| Normal GLP-1 (≥2.21 pg/L) | 8 (40%) | 18 (90%) | ||
| Post-glucose loading state | ||||
| Low 1hGLP-1 (<2.57 pg/L) | 10 (50%) | 3 (15%) | 5.667 (1.254-25.606) | 0.018 |
| Normal 1hGLP-1 (≥2.57 pg/L) | 10 (50%) | 17 (85%) | ||
| Difference (∆) | ||||
| Low ∆GLP-1 (<0.029 pg/L) | 2 (10%) | 2 (10%) | 1.00 (0.127-7.893) | 1.0 |
| Normal ∆GLP-1 (≥0.029 pg/L) | 18 (90%) | 18 (90%) | ||
T2DM, type 2 diabetes mellitus; NGT, normal glucose tolerance; FGLP-1, fasting GLP-1; 1hGLP-1, 1 h after glucose loading GLP-1; DGLP-1, responses of GLP-1 after loading.