Table 2.
Expression of genes encoding pancreatic acinar cell secretory- and related proteins
| PRSS1 | CLPS | CTRB1 | PNLIP | CPA1 | CEL | CELA3A | PLA2G1B | CTRC | CELA2A | |
|---|---|---|---|---|---|---|---|---|---|---|
| N1 | 20.6 | 20.4 | 20.0 | 20.0 | 19.9 | 19.1 | 19.0 | 18.6 | 18.8 | 18.5 |
| N2 | 20.8 | 20.3 | 20.3 | 20.2 | 19.9 | 19.2 | 19.2 | 18.8 | 18.3 | 18.5 |
| N3 | 20.4 | 20.0 | 19.9 | 19.7 | 19.7 | 18.9 | 18.8 | 18.3 | 18.0 | 18.5 |
| N4 | 20.1 | 19.5 | 19.8 | 19.3 | 19.7 | 18.6 | 18.3 | 18.0 | 18.3 | 17.3 |
| N5 | 20.7 | 20.1 | 20.3 | 20.0 | 19.9 | 19.1 | 18.7 | 19.0 | 18.9 | 18.5 |
| P1 | 13.4 | 12.8 | 12.8 | 12.4 | 12.0 | 11.2 | 11.2 | 10.4 | 10.3 | 10.3 |
| P2 | 13.9 | 13.2 | 13.2 | 12.8 | 12.6 | 11.7 | 11.6 | 10.9 | 10.8 | 10.7 |
| P3 | 14.4 | 13.3 | 14.1 | 13.5 | 13.4 | 12.4 | 12.1 | 11.6 | 11.8 | 10.9 |
| P4 | 14.3 | 13.2 | 14.0 | 13.4 | 13.3 | 12.3 | 11.9 | 11.5 | 11.7 | 10.8 |
| P5 | 13.8 | 13.2 | 13.2 | 12.8 | 12.5 | 11.6 | 11.6 | 10.8 | 10.7 | 10.7 |
| P6 | 14.0 | 13.4 | 13.4 | 13.0 | 12.7 | 11.8 | 11.9 | 11.0 | 10.9 | 10.9 |
| Mean N | 20.6 | 20.1 | 20.1 | 19.9 | 19.8 | 19.0 | 18.8 | 18.6 | 18.5 | 18.3 |
| Mean P | 14.0 | 13.2 | 13.5 | 13.0 | 12.8 | 11.9 | 11.7 | 11.1 | 11.1 | 10.7 |
| Log2 FC | 6.4 | 6.9 | 6.6 | 6.8 | 7.0 | 7.1 | 7.1 | 7.5 | 7.3 | 7.6 |
The normalized logarithmic expression of the ten most highly expressed genes in normal pancreas tissues for all five control- (N) and six PDAC (P) sequencing libraries. All genes encode pancreas-specific proteins and are homogenously, highly expressed across all control libraries and more than ~100-fold decreased in all PDAC tissues.