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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Hear Res. 2015 Jan 20;322:212–223. doi: 10.1016/j.heares.2015.01.006

Figure 3.

Figure 3

Array placement across patients in the first AMI clinical trial. For each patient, the parasagittal (top, gray box) and axial (bottom, below gray box) sections show the location and orientation of the array within the midbrain. Arrow in parasagittal section points to the caudorostral location of the array and the corresponding axial section below. The black line (or dot for AMI-2 and AMI-5) representing the array in each section corresponds to the trajectory of the array across several superimposed CT-MRI slices. ALS, anterolateral system; BIC, brachium of inferior colliculus; CIC, commissure of inferior colliculus; IC, inferior colliculus; ICC, inferior colliculus central nucleus; ICD, inferior colliculus dorsal nucleus; LL, lateral lemniscus; PAG, periaqueductal gray; SC, superior colliculus. Anatomical directions: C, caudal; D, dorsal; R, rostral; V, ventral. Further details of the reconstruction technique, anatomy of the midbrain, and AMI surgery are presented in (Lim et al., 2007b; Samii et al., 2007). Only AMI-3 was properly implanted into the target region of the ICC with the array aligned along its tonotopic axis. A portion of this figure was taken from (Lim et al., 2007b) and reprinted with permission from the Society for Neuroscience.