Table 1.
The expression of cytokines in the supernatant of each group (ELISA, pg/mL).
| Control | HG | M1 model | Mannitol | VD | M2 model | |
|---|---|---|---|---|---|---|
| TNF-α | 660.84 ± 3.21 | 960.82 ± 1.99* | 1057.64 ± 11.42* | 680.14 ± 10.38 | 802.00 ± 11.37# | 765.20 ± 33.76# |
| IL-12 | 7.11 ± 1.54 | 20.45 ± 3.43* | 26.04 ± 0.56* | 9.60 ± 0.91 | 12.45 ± 0.86# | 11.87 ± 0.56# |
| IL-10 | 21.47 ± 3.83 | 27.85 ± 1.14 | 31.19 ± 0.68 | 23.48 ± 2.03 | 81.40 ± 3.91# | 90.47 ± 2.22# |
Control: 11.1 mM glucose; HG: 25 mM glucose; M1 model: 100 U/mL IFNγ + 5 ng/mL LPS; VD: 25 mM glucose + 10−8 mol/L 1,25(OH)2D3; M2 model: 10 ng/mL IL-4. Data are presented as the mean ± SD (n = 3-4 per group). * P < 0.05 versus control; # P < 0.05 versus HG.