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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Cephalalgia. 2014 Nov 3;35(9):807–815. doi: 10.1177/0333102414557703

Table 2.

Initial Treatment with Parenteral Medication by Headache Diagnosis – alone or in initial combination

Initial Medication Given: All Primary Headache (N = 574)
n (% of total)
Headache NOS (N = 420)
n (% of total)
Migraine (N = 138)
n (% of total)
Opiates: 131 (22.8) 108 (25.7) 19 (13.8)
 •Morphine 73 (12.7) 63 (15.0) 8 (5.8)
 •Dilaudid 57 (9.9) 44 (10.5) 11 (8.0)
 •Fentanyl 1 (0.2) 1 (0.2) 0 (0)
Non-Opiate First-Line Recommended:1 303 (52.6) 216 (51.4) 79 (57.2)
 •Metochlopramide 142 (24.7) 107 (25.5) 32 (23.2)
 •NSAIDs (Keterolac) 97 (16.9) 60 (14.3) 35 (25.4)
 •Proochloperazine 69 (12.0) 52 (12.4) 15 (10.9)
 •Triptans or DHE 11 (1.9) 4 (1.0) 6 (4.4)
 •Acetaminophen 1 (0.2) 1 (0.2) 0 (0)
Other Non-Opiate Medications:2 140 (24.4) 99 (23.6) 40 (29.0)
1

Does not include Opiate combinations. There was no use of Chlorpromazine or IV Aspirin in our cohort.

2

Does not include Opiate combinations. Other medications given without concurrent parenteral headache medications included (in frequency order): Other Anti-emetics (Ondansetron and Promethazine), Benzodiazepines, and Antihistamines.